Q: When should a mole or other skin lesion be biopsied?

A: There are several characteristics of skin lesions that can be concerning for cancer. Size greater than 6 mm across, border irregularity, asymmetry, color variation and variation in the thickness of the lesion can be concerning and warrant biopsy. I have identified several skin cancers this way, allowing for expeditious referral to cancer specialists. Biopsies can save lives.